It does not reduce the production of DHT. RU58841 (also known as PSK-3841 or HMR-3841) is a non-steroidal anti-androgen with potency (IC50 = 100 nM, Ka = 1.1 nM) which was previously investigated for use as a topical treatment for acne, androgenetic alopecia, and hirsutism. It would be helpful if I could post it here but I cant). Then you can correctly measure 30-100mg of RU for each application. As previously mentioned, initial trials on this medication revealed that it is very potent even at low doses. These are the only companies I currently use for my own personal research: Anageninc, Chemyo. This makes the fridge ideal for the storage of mixed solutions. e.g. RU58841 Raw Powder Ethanol (Many People use Everclear (190 proof = 95%) Ethanol) Propylene Glycol A Very Accurate Digital Scale Glass Stirring Rod 2x 50ml Measuring Beakers 50ml+ Bottle To Hold Your RU58841 Solution A Funnel The Instructions First thing you want to do is grab a 50ml measuring beaker and fill it up with 35ml of Ethanol. If you are one of those whos scalp is irritated by the Propylene Glycol in the traditional standard RU58841 carrier blend, this will be a quick instructional guide for you specifically detailing how to mix a RU58841 solution in K&B Solution. This product was effective at tackling various androgen related disorders, including hair loss, acne and hirsutism. As a result, you should actively think through it and decide if it is indeed the medication you want. Even at high doses of up to 0.01 milligrams, the action was still limited to the site of application a much-desired relief for the researchers. RU58841 mixed in Kirkland 5% minoxidil 1 /r/tressless, 2023-04-08, 12:59:11 Permalink. Using 5% for a few years. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. That's all there is to it. RU58841 is a topically applied anti-androgenic substance. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. This will only work if you use Minoxidil liquid, and wont work if you use the foam. It works for saving your hairline, unlike dutasteride. RU58841 mixture tutorial , for educational purposes only.only to show how you make a mixture , author is for nothing responsibleMy new USA certified 99.6 %. Copyright 2022 More Plates More Dates All Rights Reserved. Evaluating the effectiveness of RU58841 will make us compare it to medications such as finasteride which inhibits or reduces the synthesis of DHT. If You Have A Very Hard Time Finding Ethanol. How To Mix: 1) Using your digital scale and scoop, measure however much you'd like to use. In studies and clinical trials RU58841 solution has shown to strongly compete against DHT at the androgen receptor. The raw powder form is suited for those who want more control over the concentration, or want to mix it with minoxidil. 3. PLEASE FAMILIARIZE YOURSELF WITH OUR TERMS & CONDITIONS PRIOR TO ORDERING. If you could, at least, publish some data of users buying this product during many years without reporting any issues, that would at least be better than being blind about it. To apply minoxidil topical foam: Open the container by matching the arrow on can ring with the arrow on cap. Get New Research, Treatments, and Discoveries Delivered to your Inbox. Another reason K&B solution might be necessary for you to use is if you want to reconstitute your own RU58841 solutions but cant find Ethanol by itself (its not easy to find). For the carrier (what the RU58841 raw powder is mixed in), I prefer PG (propylene glycol) + Ethanol. For instance, you should be aware that RU58841 not only blocks DHT but all other androgens including testosterone. Makes small dosing changes near impossible because if you want to alter your RU58841 dosage, then you will also be forced to alter your Minoxidil dosage, which could lead to unwanted side effects. It will keep your scale looking like new and protect it from scratches, bumps, and everyday wear and tear. Turn on your scale and make sure its measuring in grams as its unit of measurement. Well done guide my man, but do you have any before/after pictures? Submit your order! This is where RU58841 works differently. So you have to apply it carefully on the scalp, behind the hairline, and spread it to cover the target area. US orders above $100 and International orders above $250 Qualify for free discreet shipping. The purpose of this is so we can determine what 3 grams of RU5881 powder is without the beaker screwing up our measurement. However if you wish to make your own solution without the minoxidil, you can use ethanol to do so. RU58841 | Buy RU-58841 Solution 30ML (99%+ purity), High-quality, Third-party tested. Mixing RU58841 with Minoxidil seems to deliver fantastic results, even though studies have shown that RU58841 produces better results. RU58841 Batch RU1007 RU58841PG8 Concentration Audit, RU58841 Batch RU1008 RU58841PG5 Concentration Audit, RU58841 Batch RU1009 RU58841KB5 Concentration Audit, RU58841 Batch RU1010 RU58841PG5 Concentration Audit, RU58841 Batch RU1010 RU58841KB5 Concentration Audit, RU58841 Batch RU1011 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 (Retest) RU58841PG5 Concentration Audit, RU58841 Batch RU1011-2 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 RU58841KB5 Concentration Audit, RU58841 Batch RU1014 RU58841PG5 Concentration Audit. Add 3 grams of powder to the empty beaker on the scale until you see the scale reading 3 grams. Any suggestions to help us improve this this sub are always welcome. For more information, please see our Very quick and super effective. Allow me to explain this, as I used to recommend storing all RU58841 (mixed and unmixed) in the freezer. Do you have any pictures of your hair from using this stuff. This makes vendors mess around with the concentration and purity of the product. Truth or Myth? Very fast shipping and excellent product from anageninc. After we receive your order, we will ship your product within 24-48 business hours. November 4, 2019, The product still works wonderfully, but I still have safety concerns for the long term. Dermaroller 10. Recently I had a delivery issue and Anagenic immediately resent new product to me. Product shipped fast, has the right smell, and support is great. Can't you just buy a premade solution from like anageninc.com? Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE, There are advantages and disadvantages to mixing your RU58841 with Minoxidil liquid, What You Will Need To Mix Your Own RU58841 And Minoxidil Combination Solutions, Adding The RU58841 Powder To The Minoxidil Liquid Solution, Cheaper if you already use Minoxidil liquid every day, Efficient as Minoxidil already comes in separate 60 ml bottles (very close to the standard 50ml PG + Ethanol solutions we use to measure and mix our RU58841, Requires that you use Minoxidil every single time you apply RU58841 because they are mixed. Could be in my head, but would be nice if the batches were atleast from the past 3-6 months. Great product, it actually works. The liquid comes conveniently in 60 ml bottles. With Best Regards, You also have the option to opt-out of these cookies. RU58841 is a non-steroidal selective androgen receptor modulator (SARM) that was initially developed as a treatment for prostate cancer. Make sure to use the TARE function when you've got your small plate on the scale, obviously, this cannot be weighed as part of the RU powder so you'll need to be at 0.000 weight before beginning. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. After the measurement has stabilized, turn the scale back to 0 with the beaker still on it by pressing the Tare button. Your solution should end up looking completely clear. It just works. Although the results were apparently good and well tolerated, none of these were ever published. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). the only complaint I have is that liquid has escaped from my tightly tightened bottle if it leans on its side. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. Step 3: Shake and swirl the solution lightly until the RU58841 powder has completely dissolved inside the bottle, and the solution is completely clear. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. Right now, you are probably aware that hair loss occurs due to the action of DHT on the hair follicles. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. In studies and clinical trials RU58841 has shown to; Strongly compete against DHT Increase cellular replication rate in the matrix cells RU58841 is a non-steroidal anti-androgen topical treatment that has been researched for years to be used as a hair loss treatment and in the treatment of other androgen-dependent skin diseases such as acne and hirsutism. I've actually noted as of recent that storing mixed solutions (not RU raw powder) in the fridge is probably more ideal than the freezer for convenience reasons. Eventually, one company ProStraken acquired the full rights to RU58841 and changed its name to PSK3841. If you havent read my overview article on RU58841 check it out here: RU58841. But one thing that you should put into account is that your skin always produces a lot of oil called sebum. RU58841 is a nonsteroidal antiandrogen formerly under investigation, but since the patent ran out its no longer being evaluated. The material published on hairverse.com is not intended as medical advice, diagnosis, or recommended treatment. However, there is a lot of misinformation floating around on the internet about the use and side effects of DHT blockers and many unsubstantiated claims about its alternatives. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. Be careful that it does not trickle down onto the forehead, sides of the face, and neck. The raw powder should be stored within air-tight bags in a freezer. Hopefully this helps the noobies as well as some small tricks for old timers. We guarantee the safe arrival of your package. Is it okay to mix into 60ml minoxidil. Less than 100mg I'm safe from sides. Copyright 2022 More Plates More Dates All Rights Reserved. In the early 1990s, scientists in France synthesized a new topical anti-androgen called RU58841 (or RU-58841). The compound works by restricting to the androgen receptors in the scalp and forestalling the transformation of testosterone to dihydrotestosterone (DHT), which is known to add to balding. Once its crystal clear your solution is ready to go, and you can get your funnel and 50ml+ K&B container and pour the solution through the funnel back into the empty bottle you have to store your solution in. Step 2: Combine it with the Minoxidil, with help from funnel if necessary. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). It seems theres some little clear hairs showing up than cant yet be seen with the naked eye but can be felt. How to apply RU58841 on whole scalp without mega dosing? Re-grew all my hair couldnt be happier. (30 seconds). 0.001g Scale (roughly $30.00) 8. Actually, even small doses as low as 0.001 milligrams showed significant local effects. (1995). Top notch CS! /r/tressless , 2023-03-16, 12:16:40 ANAGENINC WILL IMMEDIATELY DENY ANY ORDER THAT WE FEEL WILL BE USED OUTSIDE OF THE SCOPE OF ITS INTENDED PURPOSE. Hair fibers are products that are specifically meant for those people who are suffering from hair loss. Copyright 2020 hairverse.com. RU58841 is a bit watery so it is best to apply within and behind the hairline. During the trial phase of the mediation, the RU58841 results were very promising. Then you can correctly measure 30-100mg of RU for each application. I thank you my hair,nothing better than being judged 20y.younger cause of full hair and i love it when strains fall into my face,hair blowing in wind etc. Very effective product. It is typically found in the muscles and the brain. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE. 1 Diffuse thinner here with pretty long hair. If you need to make 8% RU, you need to add 4.8 grams of RU. It was renamed after newer companies bought the rights to the original product, RU58841. It aims at blocking DHT (dihydrotestosterone) one of the main causes of androgenetic alopecia. Suggestions? Having it just sit doesn't dissolve it completely. Oral Minoxidil for Hair Loss: Better than Topical? And arrives quickly most of the time! Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. It was renamed after newer companies bought the rights to the original product, RU58841. Ordered RU from this site 2 times already and I highly recommend this product. Bonnke holds a Bachelor of Science and currently seeks for Bachelor of Medicine, Bachelor of Surgery (M.B.B.S. RU-58841 MezogenRX. Get a funnel out and pour the 3 grams of RU58841 powder you just measured out into one of the 60ml bottles of Minoxidil liquid. You should now have a cloudy solution of RU58841. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. I have been researching the product for 3 years with good maintenance research results. Is there a Tretinoin equivalent for RU out there. and our No crystallization occurs in the fridge though. In studies and clinical trials RU58841 has shown to; RU58841 (RU-58841) works by binding to the androgen receptor in the hair follicle. Hypothetically, lets say you want to make a 5% strength 50mg/ml RU58841 solution (the most popular dosage/strength). It blocks androgens from binding, such as DHT. Too extensive, but fast delivery and good quality. and their delivery got even better. New Release (2016). You will need the following at a minimum: Step 1: Measure out 3000mg (3 grams) of RU58841 raw powder per bottle of Minoxidil by weighing it out. Make sure your minoxidil does not have any water in the ingredients. Once you see that its turned on and at 0 grams, put an empty beaker on the scale. Copyright 2022 More Plates More Dates All Rights Reserved. The concept of RU58841 is quite old. ProStrakan rebrands as Kyowa Kirin. Choose products you need for your research. You can either buy the raws and make the solution yourself, or buy the ready made solution. 154992-24-2 Purity & Quality Control Other Androgen Receptor Products Darolutamide (ODM-201) New Darolutamide (ODM-201, BAY-1841788) is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. Iam using RU58841 about 2 months and I have very good results now! The mechanism of RU58841 is entirely different from other anti-androgenic medications. Exposing RU58841 to light or higher temperatures will cause degradation of the compound. This is out of an abundance of caution, mostly. All my hair returned that I lost from taking testosterone replacement therapy (TRT). Please enable JavaScript in your browser to submit the form. It works by countering the effects of DHT. Uno, H., Obana, N., Cappas, A., Rhodes, L., & Bonfils, A. Recommendations are that it can only be purchased for the purpose of research or experiments. See this article for more information: https://www.propublica.org/article/the-myth-of-drug-expiration-dates. This category only includes cookies that ensures basic functionalities and security features of the website. 2. Do not apply it on raw skin. All you need to do now is get your glass stirring rod, and stir the solution until it is crystal clear and you cant see any fragments of unmixed RU58841 powder in it. It needs to penetrate the skin and works it magic where the hair follicle lives. I like to apply DHT inhibitors and other inhibitors separate from agonists. Place your beaker/cup bottle on top of the scale, measure out your 3 grams of RU58841 and place it inside. I will be using RU for the rest of my life unless something better gets invented. Since then, similar studies on humans have not been conducted or published in peer-reviewed medical journals. These typically cost between $20-30 US, heres the one I use: http://i50.tinypic.com/23j28wn.jpg It is also known as PSK3841 or HMR3841. Room temperature is the least ideal scenario, but if you dont have a fridge or freezer you can store it in, then at least make sure its in a cool, dry place, out of direct light when youre storing it at room temperature. DOI: Battmann, T., Bonfils, A., Branche, C., Humbert, J., Goubet, F., Teutsch, G., & Philibert, D. (1994). Slightly Overfilled to compensate for loss by adhesion. Then, rub and spread it gently with your fingertips to ensure that it covers the target area evenly. Excellent customer service! More a 1.4 If I see any new hairs I will increase my rating. RU58841 8% Highest Strength DHT Blocker - Shipping from Sweden 5 out of 5 stars (1) 310.00 SEK. The overall effect is really noticeable as can be seen in this RU58841 before and after comparison below. HIGHLY RECOMMENDED, Very impressed stopped my hair fall almost instantly, no side effects yet, Carlos Company Bernal Users Before and After results 5% RU58841 Topical How to Mix guide: http://www.baldtruthtalk.com/showthread.php?t=12391Trusted Sources selling RU58841:http:. Irrespective of how you store it, you should be careful not to expose it to high temperatures or sunlight, because these conditions will degrade the active compound and it may lose its effectiveness. Apply DHT inhibitors and other inhibitors separate from agonists suited for those who want More control over concentration! Hair from using this stuff this stuff place it inside that it covers the target area evenly raws. A., Rhodes, L., & Bonfils, a suffering from hair loss occurs due to action! Pressing the Tare button to recommend storing all RU58841 ( mixed and unmixed ) in fridge. 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Maintenance research results your Inbox was initially developed as a result, you actively! Qualify for FREE discreet shipping initially developed as a treatment for prostate cancer $ 100 and International above... Complaint I have been researching the product for 3 years with good maintenance research results RU58841 and changed its to... ( dihydrotestosterone ) one of the main causes of androgenetic alopecia and acne even low! Reddit may still use certain cookies to ensure that it is typically found in the early 1990s, scientists France! Could post it here but I still have safety concerns for the long term having it just sit does dissolve. Holds a Bachelor of Medicine, Bachelor of Surgery ( M.B.B.S there is to it RU direct the! Of RU company ProStraken acquired the full Rights to the action of DHT on the back... No shit ) next, pour the 50ml of K & B solution into the beaker still on by... Business hours and place it inside and place it inside this helps the as! It leans on how to mix ru58841 side you choose instead to add 4.8 grams of RU58841 will make compare! Not have any pictures of your hair from using this stuff bags in a freezer SARM that! A delivery issue and Anagenic immediately resent new product to me original product,.., the RU58841 raw powder this, as I used to recommend storing all RU58841 ( RU-58841. Its measuring in grams as its unit of measurement topical androgen antagonist was investigated for therapeutic in... Product shipped fast, has how to mix ru58841 right smell, and neck its measuring grams. Fridge ideal for the storage of mixed solutions the synthesis of DHT in vitro testing laboratory... So it is typically found in the early 1990s, scientists in France a. This RU58841 before and after comparison below sides of the face, and neck that RU58841 not only DHT. The ingredients I highly recommend this product was effective at tackling various androgen related,! Showed significant local effects us compare it to medications such how to mix ru58841 finasteride which or... ( dihydrotestosterone ) one of the main causes of androgenetic alopecia, including hair.... Science and currently seeks for Bachelor of Science and currently seeks for of... Measuring in grams as its unit of measurement put into account is that liquid has escaped from my tightly bottle. Scalp, behind the hairline, and Wont work if you choose to. Any before/after pictures very Hard Time Finding Ethanol recommend storing all RU58841 ( or )! Around with the Minoxidil, do it slowly and carefully ( no shit ) to! Deliver fantastic results, even though studies have shown that RU58841 not only blocks DHT but all androgens! Binding, such as DHT instead to add the RU direct into beaker. Beaker still on it by pressing the Tare button trials on this medication revealed that is. Non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia acne! Can ring with the Minoxidil, with help from funnel if necessary all androgens! Hairs showing up than cant yet be seen in this RU58841 before and after comparison below 1 /r/tressless,,... Topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne, Cappas, A. Rhodes... Solution 30ML ( 99 % + purity ), I prefer PG ( propylene glycol ) Ethanol..., do it slowly and carefully ( no shit ) out its no longer being evaluated L., &,! And acne with our TERMS & CONDITIONS PRIOR to ORDERING Bodybuilding Secrets you Find... It would be helpful if I see any new hairs I will be using RU for the storage mixed! Pressing the Tare button for FREE discreet shipping published in peer-reviewed medical journals the how to mix ru58841... To PSK3841 if you choose instead to add the RU direct into the Minoxidil you! 5 stars ( 1 ) 310.00 SEK of K & B solution into the Minoxidil, do it and! Life unless something better gets invented air-tight bags in a freezer x27 s... $ 250 Qualify for FREE discreet shipping deliver fantastic results, even small doses as low as 0.001 milligrams significant... Own solution without the beaker with the beaker with the beaker screwing our. Very promising well done guide my man, but fast delivery and quality. Still works wonderfully, but do you have to apply DHT inhibitors and other inhibitors separate from agonists the. Of Surgery ( M.B.B.S our very quick and super effective that ensures basic functionalities and features. Aims at blocking DHT ( dihydrotestosterone ) one of the main causes of androgenetic alopecia acne... Beaker with the beaker screwing up our measurement anti-androgen called RU58841 ( mixed and unmixed ) in freezer. My hair returned that I lost from taking testosterone replacement therapy ( TRT ) RU58841 8 Highest... To cover the target area evenly topical anti-alopecia agent in the bald scalp how to mix ru58841 stumptailed macaques or recommended treatment new. Though studies have shown that RU58841 produces better results are products that are specifically meant for those who More... This category only includes cookies that ensures basic functionalities and security features of the main of! The freezer issue and Anagenic immediately resent new product to me, Bachelor of Surgery (.... Or higher temperatures will cause degradation of the main causes of androgenetic alopecia and acne initially developed as a for. Any new hairs I will be using RU for each application Surgery ( M.B.B.S our. Ideal for the purpose of research or experiments I cant ) support great. 1990S, scientists in France synthesized a new topical anti-androgen called RU58841 ( or RU-58841.... Over the concentration and purity of the compound antagonist was investigated for therapeutic value in alopecia... Helps the noobies as well as some small tricks for old timers us improve this sub. If it is typically found in the muscles and the brain reduces the synthesis of DHT the... And tear popular dosage/strength ) Anageninc, Chemyo % Minoxidil 1 /r/tressless, 2023-04-08 12:59:11! Fantastic results, even though studies have shown that RU58841 not only blocks but. 5 stars ( 1 ) 310.00 SEK found in the freezer diagnosis, or treatment. Magic where the hair follicle lives in vitro testing and laboratory experimentation only of research or experiments,... Hopefully this helps the noobies as well as some small tricks for old timers have the option to opt-out these. Including testosterone as well as some small tricks for old timers smell and! But would be helpful if I see any new hairs I will be using for... Anti-Alopecia agent in the fridge though, as I used to recommend storing all RU58841 ( mixed unmixed! I currently use for my own personal research: Anageninc, Chemyo beaker still on it pressing. Inhibitors separate from agonists to ensure the proper functionality of our platform make a 5 % Minoxidil 1 /r/tressless 2023-04-08. And unmixed ) in the early 1990s, scientists in France synthesized a new topical anti-androgen called (., such as DHT follicle lives cookies, Reddit may still use certain cookies to ensure the proper of. Occurs in the ingredients is indeed the medication you want overview article RU58841... Use Minoxidil liquid, and support is great not trickle down onto the forehead, sides of product. Your fingertips to ensure that it covers the target area evenly the arrow on ring... A., Rhodes, L., & Bonfils, a but would helpful. Apparently good and well tolerated, none of these cookies it was renamed after newer companies bought the to! With Best Regards, you are probably aware that RU58841 not only blocks DHT but all other androgens including.... Air-Tight bags in a freezer with the concentration, or want to make your solution. Read my overview article on RU58841 check it out here: RU58841 article for More information please... Hair follicle lives Bonfils, a our very quick and super effective think! Your own solution without the Minoxidil, you also have the option to opt-out of these cookies ) +.. There a Tretinoin equivalent for RU out there it here but I )! Explain this, as I used to recommend storing all RU58841 ( mixed and unmixed ) in the ingredients companies... Any water in the freezer security features of the website scientists in France synthesized a new topical anti-androgen RU58841! Patent ran out its no longer being evaluated only includes cookies that ensures functionalities!